[發明專利]枯草蛋白酶變體

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• 申請號: 201310544773.1
• 申請日: 2006-07-06
• 公開（公告）號: CN103555697A
• 公開（公告）日: 2014-02-05
• 發明（設計）人: 亨麗埃特.德拉伯格;維貝克.S.尼爾森;斯蒂芬.明寧
• 申請（專利權）人: 諾維信公司
• 主分類號: C12N9/56
• 分類號: C12N9/56;C12N15/57;C11D3/386;C12R1/125
• 代理公司: 北京市柳沈律師事務所 11105
• 代理人: 羅天樂

1.枯草蛋白酶變體，其包含一個或多個選自下組的修飾：?

S9R,A15T,V68A,H120N,Q245R;?

S9R,A15T,V68A,Q245R,N252K;?

S9R,A15T,V68A,I79T,G102S,P131H,Q137H;?

S9R,V68A,S99G,Q245R,N261D;?

S9R,A15T,V68A,S99G,N261D;?

S9R,A15T,V68A,Q245R,N261D;?

S9R,A15T,V68A,H120N,P131S,Q137H,Q245M;?

S9R,A15T,V68A,I72F,S99G,Q245R,N261D;?

S9R,A15T,V68A,S99D,Q245R,N261D;?

S9R,A15T,V68A,N76I,S99G,Q245R,N261D;?

Y167A,R170S,A194P,K251R;?

Y167A,R170S,A194P,S265K;?

Y167A,R170S,A194P,V244R;?

S141E,Y167A,R170S,A194P;?

Y167A,R170S,M175I;?

Y167A,R170S,A172T;?

Y167A,R170S,A174V,M175F;?

Y167A,R170S,A172V,A174V;?

Y167A,R170S,A172E;?

Y167A,R170S,M175L;?

Y167A,R170S,A174T;?

Y167A,R170S,A174T,M175L;?

G53C,G61E;?

A98S,S99D,G100S;?

S9R,T22A,V68A,S99A,*99aD;?

S9R,P14H,R19L,N62D;?

G61P,*99aS;?

N43S,N62D;?

*96aG,P131S,V203A,A228T;?

N62D,A232C,Q236L,Q245N;?

*96aA,A98T,R247K;?

S99D,S101R,S103A,V104I,G160S,A194P,L217D;?

*61aD;?

N62D,S106A;?

V68A,S106M,N184D;?

S9R,A15T,*97aV,H120N;?

A15M,A16P,*99aD;?

*99aE,G160S,S163T,G195S,G211S,K237R,G258A,T260L;?

G23S,*99aD,A194P,S242T,Q245R;?

G100S,N173D;?

Y167A,R170S,A172E;?

A98T,Q137L,Y167A,R170S,M175L;?

*98aA,S99D;?

S99A,*99aD,V203A;?

N62D,K237R;?

V11M,N76D,L126F,K251R;?

S9F,A15L,A16P,T22I,*98aA,S99D,R170H;?

*96aA,*130aG,P131H;?

E54D,N62D;?

*98aA,*98bS,S99G,S101T;?

*100aA,*100bG,*100cS,*100dG;?

V68A,L111I;?

*98aA,R170H,Q245R;?

I35V,N62D,N183D,T224S;?

*97aG,P131S,V203A,A228T;?

S9R,R10K,P14Q,T22A,Y167A,R170S;?

S9R,*22aL,S57A,G61E,*98aA,V139L,N173S;?

P14T,N18K,Y167A,R170S;?

S9R,Q12E,P14Q,K27R,Y167A,R170S;?

N62D,R170L;?

N62D,R170S,Q245R;?

Y167A,R170S,A194P,K251R,S265K;?

P14T,N18K,Y167A,R170S,A194P;?

N62D,A151G,K237R;?

N62D,A151G,Q245R;?

N62D,A151G,K237R,Q245R;?

S103A,V104I,G159D,A232V,Q236H,Q245R;?

S9R,A15T,T22A,V139L;?

S9R,A15T,G61E,A85T,E89Q,P239L,Q245C;?

N248R;?

S9R,A15T,*22aL,V139L,N204D,Q245L;?

N218S;?

V68A,S106A,H120N;?

V68A,S106A,N252K;?

A15T,V68A,S99G,Q245R,N261D;?

V68A,S99G,Q245R,N261D;?

S9R,A15T,*22aL,V139L,S163G,N204D,Q245L;?

Q245R,N252H;?

S9R,*22aL,G61E,*97aA,M119I,Q137H,N173S和?

V68A,S106A,T213A。?